The Enjoy margarine every day project is a perfect example of how to implement taxonomies of video and images. We used both content types and taxonomy to display the content in a flexible way, each node can have both images and video attached to it.
Audio & Video
Create your own Theme from hundreds of existing themes and then customise it. This is a fantastic feature in Drupal to implement any kind of design in terms of look, feel and structure. Set up your regions such as the 12 grids responsive layout, Omega theme, very good for mobile.